Riboflavin is a B vitamin. It can be found in certain foods such as milk, meat, eggs, nuts, enriched flour, and green vegetables. Riboflavin is frequently used in combination with other B vitamins in vitamin B complex products.
Riboflavin is required for the proper development and function of the skin, lining of the digestive tract, blood cells, and many other parts of the body.
Riboflavin is used for preventing low levels of riboflavin (riboflavin deficiency), cervical cancer, and migraine headaches. It is also used for treating riboflavin deficiency, acne, muscle cramps, burning feet syndrome, carpal tunnel syndrome, and blood disorders such as congenital methemoglobinemia and red blood cell aplasia. Some people use riboflavin for eye conditions including eye fatigue, cataracts, and glaucoma.
Other uses include increasing energy levels; boosting immune system function; maintaining healthy hair, skin, mucous membranes, and nails; slowing aging; boosting athletic performance; promoting healthy reproductive function; canker sores; memory loss, including Alzheimer’s disease; ulcers; burns; alcoholism; liver disease; sickle cellanemia; and treating lactic acidosis brought on by treatment with a class of AIDS medications called NRTI drugs.
SPECIAL PRECAUTIONS AND WARNINGS
Riboflavin is LIKELY SAFE for most people when taken by mouth. In some people, riboflavin can cause the urine to turn a yellow-orange color. When taken in high doses, riboflavin might cause diarrhea, an increase in urine, and other side effects.
Pregnancy and breast-feeding: Riboflavin is LIKELY SAFE for pregnant or breast-feeding women when taken in the amounts recommended. The recommended amounts are 1.4 mg per day for pregnant women and 1.6 mg per day in breast-feeding women. Riboflavin is POSSIBLY SAFE when taken by mouth in larger doses, short-term. Some research shows that riboflavin is safe when taken at a dose of 15 mg once every 2 weeks for 10 weeks.
Hepatitis, Cirrhosis, Billary obstruction: Riboflavin absorption is decreased in people with these conditions.
- Drying medications (Anticholinergic drugs) interacts with RIBOFLAVIN
Some drying medications can affect the stomach and intestines. Taking these drying medications with riboflavin (vitamin B2) can increase the amount of riboflavin that is absorbed in the body. But it’s not known if this interaction is important.
- Medications for depression (Tricyclic antidepressants) interacts with RIBOFLAVIN
Some medications for depression can decrease the amount of riboflavin in the body. This interaction is not a big concern because it only occurs with very large amounts of some medications for depression.
- Phenobarbital (Luminal) interacts with RIBOFLAVIN
Riboflavin is broken down by the body. Phenobarbital might increase how quickly riboflavin is broken down in the body. It is not clear if this interaction is significant.
- Probenecid (Benemid) interacts with RIBOFLAVIN
Probenecid (Benemid) can increase how much riboflavin is in the body. This might cause there to be too much riboflavin in the body. But it’s not known if this interaction is a big concern.
- For treating low levels of riboflavin (riboflavin deficiency) in adults: 5-30 mg of riboflavin (Vitamin B2) daily in divided doses.
- For preventing migraine headaches: 400 mg of riboflavin (Vitamin B2) per day. It may take up to three months to get best results.
- For preventing cataracts: a daily dietary intake of approximately 2.6 mg of riboflavin (Vitamin B2) has been used. A combination of 3 mg of riboflavin (Vitamin B2) plus 40 mg of niacin daily has also been used.
- The daily recommended dietary allowances (RDAs) of riboflavin (Vitamin B2) are: Infants 0-6 months, 0.3 mg; infants 7-12 months, 0.4 mg; children 1-3 years, 0.5 mg; children 4-8 years, 0.6 mg; children 9-13 years, 0.9 mg; men 14 years or older, 1.3 mg; women 14-18 years, 1 mg; women over 18 years, 1.1 mg; pregnant women, 1.4 mg; and breastfeeding women, 1.6 mg.
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